Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

Visceral leishmaniasis is a potentially fatal disease endemic to large parts of Asia and Africa, primarily caused by the protozoan parasite Leishmania donovani. Here, we report a high-quality reference genome sequence for a strain of L. donovani from Nepal, and use this sequence to study variation i...

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Bibliografiske detaljer
Main Authors: Downing, Tim, Imamura, Hideo, Decuypere, Saskia, Clark, Taane G., Coombs, Graham H., Cotton, James A., Hilley, James D., de Doncker, Simonne, Maes, Ilse, Mottram, Jeremy C., Quail, Mike A., Rijal, Suman, Sanders, Mandy, Schönian, Gabriele, Stark, Olivia, Sundar, Shyam, Vanaerschot, Manu, Hertz-Fowler, Christiane, Dujardin, Jean-Claude, Berriman, Matthew
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227103/
https://ncbi.nlm.nih.gov/pubmed/22038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.123430.111
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