Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

Visceral leishmaniasis is a potentially fatal disease endemic to large parts of Asia and Africa, primarily caused by the protozoan parasite Leishmania donovani. Here, we report a high-quality reference genome sequence for a strain of L. donovani from Nepal, and use this sequence to study variation i...

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Main Authors: Downing, Tim, Imamura, Hideo, Decuypere, Saskia, Clark, Taane G., Coombs, Graham H., Cotton, James A., Hilley, James D., de Doncker, Simonne, Maes, Ilse, Mottram, Jeremy C., Quail, Mike A., Rijal, Suman, Sanders, Mandy, Schönian, Gabriele, Stark, Olivia, Sundar, Shyam, Vanaerschot, Manu, Hertz-Fowler, Christiane, Dujardin, Jean-Claude, Berriman, Matthew
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227103/
https://ncbi.nlm.nih.gov/pubmed/22038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.123430.111
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