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Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states
We have determined methylation state differences in the epigenomes of uncultured cells purified from human, chimpanzee, and orangutan, using digestion with a methylation-sensitive enzyme, deep sequencing, and computational analysis of the sequence data. The methylomes show a high degree of conservat...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3227095/ https://ncbi.nlm.nih.gov/pubmed/21908772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122721.111 |
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