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Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states

We have determined methylation state differences in the epigenomes of uncultured cells purified from human, chimpanzee, and orangutan, using digestion with a methylation-sensitive enzyme, deep sequencing, and computational analysis of the sequence data. The methylomes show a high degree of conservat...

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Detalhes bibliográficos
Main Authors: Martin, David I.K., Singer, Meromit, Dhahbi, Joseph, Mao, Guanxiong, Zhang, Lu, Schroth, Gary P., Pachter, Lior, Boffelli, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227095/
https://ncbi.nlm.nih.gov/pubmed/21908772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122721.111
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