A High Occurrence of Acquisition and/or Expansion of C-CBL Mutant Clones in the Progression of High-Risk Myelodysplastic Syndrome to Acute Myeloid Leukemia

The molecular pathogenesis of myelodysplastic syndrome (MDS) and its progression to secondary acute myeloid leukemia (sAML) remain to be explored. Somatic C-CBL mutations were recently described in MDS. Our study aimed to determine the role of C-CBL mutations in the progression of MDS to sAML and so...

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Autori principali: Kao, Hsiao-Wen, Sanada, Masashi, Liang, Der-Cherng, Lai, Chang-Liang, Lee, En-Hui, Kuo, Ming-Chung, Lin, Tung-Liang, Shih, Yu-Shu, Wu, Jin-Hou, Huang, Chein-Fuang, Ogawa, Seishi, Shih, Lee-Yung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226941/
https://ncbi.nlm.nih.gov/pubmed/22131879
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