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Flexibility, Diversity, and Cooperativity: Pillars of Enzyme Catalysis

This brief review discusses our current understanding of the molecular basis of enzyme catalysis. A historical development is presented, beginning with steady state kinetics and progressing through modern fast reaction methods, NMR, and single molecule fluorescence techniques. Experimental results a...

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Détails bibliographiques
Auteurs principaux: Hammes, Gordon G., Benkovic, Stephen J., Hammes-Schiffer, Sharon
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226911/
https://ncbi.nlm.nih.gov/pubmed/22029278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201486f
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