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Coupled Motions in Enzyme Catalysis

Recently, the hypothesis that protein motions are involved in enzymatic turnover has gained significant attention. We review cases where there is evidence that protein motions are rate-limiting in the overall catalytic cycle and examine experimental and theoretical evidence for how such motions enha...

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Detalhes bibliográficos
Main Authors: Nashine, Vishal C., Hammes-Schiffer, Sharon, Benkovic, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953590/
https://ncbi.nlm.nih.gov/pubmed/20729130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.07.020
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