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Coupled Motions in Enzyme Catalysis

Recently, the hypothesis that protein motions are involved in enzymatic turnover has gained significant attention. We review cases where there is evidence that protein motions are rate-limiting in the overall catalytic cycle and examine experimental and theoretical evidence for how such motions enha...

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Détails bibliographiques
Auteurs principaux: Nashine, Vishal C., Hammes-Schiffer, Sharon, Benkovic, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953590/
https://ncbi.nlm.nih.gov/pubmed/20729130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.07.020
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