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Coupled Motions in Enzyme Catalysis

Recently, the hypothesis that protein motions are involved in enzymatic turnover has gained significant attention. We review cases where there is evidence that protein motions are rate-limiting in the overall catalytic cycle and examine experimental and theoretical evidence for how such motions enha...

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Autors principals: Nashine, Vishal C., Hammes-Schiffer, Sharon, Benkovic, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953590/
https://ncbi.nlm.nih.gov/pubmed/20729130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.07.020
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