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A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

Natural products that elicit discomfort or pain represent invaluable tools for probing molecular mechanisms underlying pain sensation(1). Plant-derived irritants have predominated in this regard, but animal venoms have also evolved to avert predators by targeting neurons and receptors whose activati...

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Bibliografiske detaljer
Main Authors: Bohlen, Christopher J., Chesler, Alexander T., Sharif-Naeini, Reza, Medzihradszky, Katalin F., Zhou, Sharleen, King, David, Sánchez, Elda E., Burlingame, Alma L., Basbaum, Allan I., Julius, David
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226747/
https://ncbi.nlm.nih.gov/pubmed/22094702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10607
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