Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release

Pain-producing animal venoms contain evolutionarily honed toxins that can be exploited to study and manipulate somatosensory and nociceptive signaling pathways. From a functional screen, we have identified a secreted phospholipase A2 (sPLA2)-like protein, BomoTx, from the Brazilian lancehead pit vip...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zhang, Chuchu, Medzihradszky, Katalin F., Sánchez, Elda E., Basbaum, Allan I., Julius, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373363/
https://ncbi.nlm.nih.gov/pubmed/28265084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615484114
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