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Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A(2) homologue from Atropoides nummifer venom

Lys49 snake-venom phospholipase A(2) (PLA(2)) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural...

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Detalhes bibliográficos
Main Authors: Murakami, Mário T., Melo, Cristiane C., Angulo, Yamileth, Lomonte, Bruno, Arni, Raghuvir K.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219968/
https://ncbi.nlm.nih.gov/pubmed/16682766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106010700
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