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Explaining pathological changes in axonal excitability through dynamical analysis of conductance-based models

Neurons rely on action potentials, or spikes, to relay information. Pathological changes in spike generation likely contribute to certain enigmatic features of neurological disease, like paroxysmal attacks of pain and muscle spasm. Paroxysmal symptoms are characterized by abrupt onset and short dura...

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Main Authors: Coggan, Jay S, Ocker, Gabriel K, Sejnowski, Terrence J, Prescott, Steven A
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226740/
https://ncbi.nlm.nih.gov/pubmed/22058273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1741-2560/8/6/065002
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