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Explaining pathological changes in axonal excitability through dynamical analysis of conductance-based models

Neurons rely on action potentials, or spikes, to relay information. Pathological changes in spike generation likely contribute to certain enigmatic features of neurological disease, like paroxysmal attacks of pain and muscle spasm. Paroxysmal symptoms are characterized by abrupt onset and short dura...

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Hlavní autoři: Coggan, Jay S, Ocker, Gabriel K, Sejnowski, Terrence J, Prescott, Steven A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226740/
https://ncbi.nlm.nih.gov/pubmed/22058273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1741-2560/8/6/065002
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