Global Identification of Modular Cullin-Ring Ligase Substrates

Cullin Ring Ligases (CRLs) represent the largest E3 ubiquitin ligase family in eukaryotes and the identification of their substrates is critical to understanding regulation of the proteome. Using genetic and pharmacologic Cullin inactivation coupled with genetic (GPS) and proteomic (QUAINT) assays,...

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Main Authors: Emanuele, Michael J., Elia, Andrew E.H., Xu, Qikai, Thoma, Claudio R, Izhar, Lior, Leng, Yumei, Guo, Ailan, Chen, Yi-Ning, Rush, John, Hsu, Paul Wei-Che, Yen, Hsueh-Chi Sherry, Elledge, Stephen J
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226719/
https://ncbi.nlm.nih.gov/pubmed/21963094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.019
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