Raloxifene and Desmethylarzoxifene Block Estrogen-Induced Malignant Transformation of Human Breast Epithelial Cells

There is association between exposure to estrogens and the development and progression of hormone-dependent gynecological cancers. Chemical carcinogenesis by catechol estrogens derived from oxidative metabolism is thought to contribute to breast cancer, yet exact mechanisms remain elusive. Malignant...

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Main Authors: Kastrati, Irida, Edirisinghe, Praneeth D., Hemachandra, L-P-Madhubani P., Chandrasena, Esala R., Choi, Jaewoo, Wang, Yue-Ting, Bolton, Judy L., Thatcher, Gregory R. J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226622/
https://ncbi.nlm.nih.gov/pubmed/22140478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027876
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