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Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease

Transporters located on the sinusoidal and canalicular membranes of hepatocytes regulate the efflux of drugs and metabolites into blood and bile, respectively. Changes in the expression or function of these transporters during liver disease may lead to a greater risk of adverse drug reactions. Nonal...

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Bibliographic Details
Main Authors: Hardwick, Rhiannon N., Fisher, Craig D., Canet, Mark J., Scheffer, George L., Cherrington, Nathan J.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226375/
https://ncbi.nlm.nih.gov/pubmed/21878559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041012
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