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Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease

Transporters located on the sinusoidal and canalicular membranes of hepatocytes regulate the efflux of drugs and metabolites into blood and bile, respectively. Changes in the expression or function of these transporters during liver disease may lead to a greater risk of adverse drug reactions. Nonal...

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Main Authors: Hardwick, Rhiannon N., Fisher, Craig D., Canet, Mark J., Scheffer, George L., Cherrington, Nathan J.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226375/
https://ncbi.nlm.nih.gov/pubmed/21878559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041012
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