Complex N-Acetylation of Triethylenetetramine

Triethylenetetramine (TETA) is an efficient copper chelator that has versatile clinical potential. We have recently shown that spermidine/spermine-N(1)-acetyltransferase (SSAT1), the key polyamine catabolic enzyme, acetylates TETA in vitro. Here, we studied the metabolism of TETA in three different...

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Autors principals: Cerrada-Gimenez, Marc, Weisell, Janne, Hyvönen, Mervi T., Hee Park, Myung, Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226374/
https://ncbi.nlm.nih.gov/pubmed/21878558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.041798
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