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Retargeted Clostridial Neurotoxins as Novel Agents for Treating Chronic Diseases

[Image: see text] Botulinum neurotoxin (BoNT) A and B are used to treat neuropathic disorders; if retargeted, these agents could be used to treat medical conditions that involve secretion from nonneuronal cells. Here, we report novel strategies for successfully retargeting BoNTs, and also tetanus ne...

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Main Authors: Yeh, Felix L., Zhu, Yiming, Tepp, William H., Johnson, Eric A., Bertics, Paul J., Chapman, Edwin R.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2011
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226321/
https://ncbi.nlm.nih.gov/pubmed/22047069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201490t
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