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Insoluble cellular prion protein and its association with prion and Alzheimer diseases
The soluble cellular prion protein (PrP(C)) is best known for its association with prion disease (PrD) through its conversion to a pathogenic insoluble isoform (PrP(Sc)). However, its deleterious effects independent of PrP(Sc) have recently been observed not only in PrD but also in Alzheimer disease...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226044/ https://ncbi.nlm.nih.gov/pubmed/21847014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16894 |
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