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(Ctm)PrP and ER stress: A neurotoxic mechanism of some special PrP mutants
The pathogenic agent is hypothesized to be PrP(Sc) in prion diseases. However, little accumulation of PrP(Sc) is repeatedly observed in some kinds of natural and experimental prion diseases, including some special genetic human prion diseases. One of the specific topology forms of PrP, (Ctm)PrP, rep...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226035/ https://ncbi.nlm.nih.gov/pubmed/21795854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16327 |
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