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In Vivo and In Vitro Neurotoxicity of the Human Prion Protein (PrP) Fragment P118–135 Independently of PrP Expression
We recently demonstrated that the 118–135 putative transmembrane domain of prion protein (PrP) exhibited membrane fusogenic properties and induced apoptotic neuronal cell death of rat cortical neurons, independently of its aggregation state. The aim of the present study was to analyze the in vivo ne...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741883/ https://ncbi.nlm.nih.gov/pubmed/12533606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-02-00462.2003 |
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