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Biochemical and biophysical characterization of humanized IgG1 produced in Pichia pastoris
The first full length IgG produced in Pichia pastoris was reported in late 1980. However, use of a wild-type Pichia expression system to produce IgGs with human-like N-linked glycans was not possible until recently. Advances in glycoengineering have enabled organisms such as Pichia to mimic human N-...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225849/ https://ncbi.nlm.nih.gov/pubmed/22048694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.5.16891 |
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