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Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

The pathogenic origin of autoimmune diseases can be traced to both genetic susceptibility and epigenetic modifications arising from exposure to the environment. Epigenetic modifications influence gene-expression and alter cellular functions without modifying the genomic sequence. CpG-DNA methylation...

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Detalles Bibliográficos
Main Authors: Hedrich, Christian M., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225699/
https://ncbi.nlm.nih.gov/pubmed/21885342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.07.005
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