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Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases
The pathogenic origin of autoimmune diseases can be traced to both genetic susceptibility and epigenetic modifications arising from exposure to the environment. Epigenetic modifications influence gene-expression and alter cellular functions without modifying the genomic sequence. CpG-DNA methylation...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225699/ https://ncbi.nlm.nih.gov/pubmed/21885342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.07.005 |
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