Localization and Activity of the Calcineurin Catalytic and Regulatory Subunit Complex at the Septum is Essential for Hyphal Elongation and Proper Septation in Aspergillus fumigatus

Calcineurin, a heterodimer composed of the catalytic (CnaA) and regulatory (CnaB) subunits, plays key roles in growth, virulence, and stress responses of fungi. To investigate the contribution of CnaA and CnaB to hyphal growth and septation, ΔcnaB and ΔcnaA ΔcnaB strains of A. fumigatus were constru...

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Bibliographic Details
Main Authors: Juvvadi, Praveen Rao, Fortwendel, Jarrod R., Rogg, Luise E., Burns, Kimberlie A., Randell, Scott H., Steinbach, William J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225650/
https://ncbi.nlm.nih.gov/pubmed/22066998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07886.x
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