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Kin1 Kinase Localizes at the Hyphal Septum and is Dephosphorylated by Calcineurin but is Dispensable for Septation and Virulence in the Human Pathogen Aspergillus fumigatus

Studies in yeasts have implicated the importance of Kin1 protein kinase, a member of the eukaryotic PAR1/MARK/MELK family, in polarized growth, cell division and septation through coordinated activity with the phosphatase, calcineurin. Kin1 is also required for virulence of the fungal pathogens Cryp...

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Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Juvvadi, Praveen R., Cole, D. Christopher, Falloon, Katie, Waitt, Greg, Soderblom, Erik J., Moseley, M. Arthur, Steinbach, William J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206501/
https://ncbi.nlm.nih.gov/pubmed/30292408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.09.186
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