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Mild thalassemia: the result of interactions of alpha and beta thalassemia genes

Homozygous thalassemia is due to inherited unbalanced synthesis of the α- or β-chains of hemoglobin. Clinical severity may be in part related to the extent of α:β imbalance. Two families are presented that illustrate this concept. Thalassemia in these individuals was evaluated by clinical and geneti...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Kan, Yuet Wai, Nathan, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5443168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106274
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