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Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells

The study of how human embryonic stem cells (hESCs) differentiate into insulin-producing beta cells has two-fold significance: first, it provides an in vitro model system for the study of human pancreatic development, and second, it serves as a platform for the ultimate production of beta cells for...

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Autori principali: Xu, Xiaofang, Browning, Victoria, Odorico, Jon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225072/
https://ncbi.nlm.nih.gov/pubmed/21855631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2011.08.001
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