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Studies on the biological activity of porcine proinsulin

The biological activity of purified porcine proinsulin was investigated in rats. In vivo studies revealed that proinsulin produced a hypoglycemic response similar to insulin but of lesser magnitude. Hypophysectomized and adrenalectomized animals proved to be more sensitive to proinsulin than normal....

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lazarus, Norman R., Penhos, Juan C., Tanese, Tomio, Michaels, Leslie, Gutman, Raul, Recant, Lillian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5416410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106258
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