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Studies on the biological activity of porcine proinsulin

The biological activity of purified porcine proinsulin was investigated in rats. In vivo studies revealed that proinsulin produced a hypoglycemic response similar to insulin but of lesser magnitude. Hypophysectomized and adrenalectomized animals proved to be more sensitive to proinsulin than normal....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Lazarus, Norman R., Penhos, Juan C., Tanese, Tomio, Michaels, Leslie, Gutman, Raul, Recant, Lillian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1970
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5416410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106258
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