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Translesion DNA synthesis in the context of cancer research

During cell division, replication of the genomic DNA is performed by high-fidelity DNA polymerases but these error-free enzymes can not synthesize across damaged DNA. Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avo...

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Bibliografische gegevens
Hoofdauteurs: Knobel, Philip A, Marti, Thomas M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224763/
https://ncbi.nlm.nih.gov/pubmed/22047021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-39
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