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Translesion DNA synthesis in the context of cancer research
During cell division, replication of the genomic DNA is performed by high-fidelity DNA polymerases but these error-free enzymes can not synthesize across damaged DNA. Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224763/ https://ncbi.nlm.nih.gov/pubmed/22047021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-39 |
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