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Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

BACKGROUND: Aberrant promoter DNA methylation has been reported in childhood acute lymphoblastic leukaemia (ALL) and has the potential to contribute to its onset and outcome. However, few reports demonstrate consistent, prevalent and dense promoter methylation, associated with tumour-specific gene s...

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Bibliographic Details
Main Authors: Weeks, Robert J, Kees, Ursula R, Song, Sarah, Morison, Ian M
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224738/
https://ncbi.nlm.nih.gov/pubmed/20573277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-163
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