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Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

BACKGROUND: Aberrant promoter DNA methylation has been reported in childhood acute lymphoblastic leukaemia (ALL) and has the potential to contribute to its onset and outcome. However, few reports demonstrate consistent, prevalent and dense promoter methylation, associated with tumour-specific gene s...

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Autori principali: Weeks, Robert J, Kees, Ursula R, Song, Sarah, Morison, Ian M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224738/
https://ncbi.nlm.nih.gov/pubmed/20573277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-163
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