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Predicting Bevirimat resistance of HIV-1 from genotype

BACKGROUND: Maturation inhibitors are a new class of antiretroviral drugs. Bevirimat (BVM) was the first substance in this class of inhibitors entering clinical trials. While the inhibitory function of BVM is well established, the molecular mechanisms of action and resistance are not well understood...

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Autori principali: Heider, Dominik, Verheyen, Jens, Hoffmann, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224585/
https://ncbi.nlm.nih.gov/pubmed/20089140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-37
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