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Prediction of Co-Receptor Usage of HIV-1 from Genotype
Human Immunodeficiency Virus 1 uses for entry into host cells a receptor (CD4) and one of two co-receptors (CCR5 or CXCR4). Recently, a new class of antiretroviral drugs has entered clinical practice that specifically bind to the co-receptor CCR5, and thus inhibit virus entry. Accurate prediction of...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855328/ https://ncbi.nlm.nih.gov/pubmed/20419152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000743 |
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