Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype

Drug resistance testing has been shown to be beneficial for clinical management of HIV type 1 infected patients. Whereas phenotypic assays directly measure drug resistance, the commonly used genotypic assays provide only indirect evidence of drug resistance, the major challenge being the interpretat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beerenwinkel, Niko, Schmidt, Barbara, Walter, Hauke, Kaiser, Rolf, Lengauer, Thomas, Hoffmann, Daniel, Korn, Klaus, Selbig, Joachim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2002
Pynciau:
Physical Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC123057/
https://ncbi.nlm.nih.gov/pubmed/12060770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112177799
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