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Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype

Drug resistance testing has been shown to be beneficial for clinical management of HIV type 1 infected patients. Whereas phenotypic assays directly measure drug resistance, the commonly used genotypic assays provide only indirect evidence of drug resistance, the major challenge being the interpretat...

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Detalhes bibliográficos
Main Authors: Beerenwinkel, Niko, Schmidt, Barbara, Walter, Hauke, Kaiser, Rolf, Lengauer, Thomas, Hoffmann, Daniel, Korn, Klaus, Selbig, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123057/
https://ncbi.nlm.nih.gov/pubmed/12060770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112177799
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