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Structure–Activity Analysis and Cell-Based Optimization of Human Galactokinase Inhibitors
[Image: see text] Classic galactosemia is a rare human disease associated with the accumulation of a toxic level of galactose-1-phosphate (gal-1P) caused by the inherited deficiency of galactose-1-phosphate uridyltransferase (GALT) activity. To reduce the toxic level of gal-1P in patients, we have i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224021/ https://ncbi.nlm.nih.gov/pubmed/22125663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200131j |
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