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Structure–Activity Analysis and Cell-Based Optimization of Human Galactokinase Inhibitors

[Image: see text] Classic galactosemia is a rare human disease associated with the accumulation of a toxic level of galactose-1-phosphate (gal-1P) caused by the inherited deficiency of galactose-1-phosphate uridyltransferase (GALT) activity. To reduce the toxic level of gal-1P in patients, we have i...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Odejinmi, Sina I., Rascon, Rafael G., Tang, Manshu, Vankayalapati, Hariprasad, Lai, Kent
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2011
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224021/
https://ncbi.nlm.nih.gov/pubmed/22125663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200131j
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