Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer

Fatty acid synthase (FASN), a key metabolic enzyme for liponeogenesis highly expressed in several human cancers, displays oncogenic properties such as resistance to apoptosis and induction of proliferation when overexpressed. To date, no mechanism has been identified to explain the oncogenicity of F...

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Detaylı Bibliyografya
Asıl Yazarlar: Fiorentino, Michelangelo, Zadra, Giorgia, Palescandolo, Emanuele, Fedele, Giuseppe, Bailey, Dyane, Fiore, Christopher, Nguyen, Paul L., Migita, Toshiro, Zamponi, Raffaella, Di Vizio, Dolores, Priolo, Carmen, Chandan, Sharma, Xie, Wanling, Hemler, Martin E., Mucci, Lorelei, Giovannucci, Edward, Finn, Stephen, Loda, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223737/
https://ncbi.nlm.nih.gov/pubmed/18838960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.97
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