Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer

BACKGROUND: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN. METHODS: We used immortalized human prostate epithelial cells (iPrECs), androgen receptor–overexpressing iPrECs (AR-iPrEC),...

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Päätekijät: Migita, Toshiro, Ruiz, Stacey, Fornari, Alessandro, Fiorentino, Michelangelo, Priolo, Carmen, Zadra, Giorgia, Inazuka, Fumika, Grisanzio, Chiara, Palescandolo, Emanuele, Shin, Eyoung, Fiore, Christopher, Xie, Wanling, Kung, Andrew L., Febbo, Phillip G., Subramanian, Aravind, Mucci, Lorelei, Ma, Jing, Signoretti, Sabina, Stampfer, Meir, Hahn, William C., Finn, Stephen, Loda, Massimo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2009
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664091/
https://ncbi.nlm.nih.gov/pubmed/19318631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp030
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