Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer

Fatty acid synthase (FASN), a key metabolic enzyme for liponeogenesis highly expressed in several human cancers, displays oncogenic properties such as resistance to apoptosis and induction of proliferation when overexpressed. To date, no mechanism has been identified to explain the oncogenicity of F...

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書誌詳細
主要な著者: Fiorentino, Michelangelo, Zadra, Giorgia, Palescandolo, Emanuele, Fedele, Giuseppe, Bailey, Dyane, Fiore, Christopher, Nguyen, Paul L., Migita, Toshiro, Zamponi, Raffaella, Di Vizio, Dolores, Priolo, Carmen, Chandan, Sharma, Xie, Wanling, Hemler, Martin E., Mucci, Lorelei, Giovannucci, Edward, Finn, Stephen, Loda, Massimo
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223737/
https://ncbi.nlm.nih.gov/pubmed/18838960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.97
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