Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset

Wilms' tumors (WTs) originate from metanephric blastema cells that are unable to complete differentiation, resulting in triphasic tumors composed of epithelial, stromal and blastemal cells, with the latter harboring molecular characteristics similar to those of the earliest kidney development s...

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Detalhes bibliográficos
Main Authors: Maschietto, M, Trapé, A P, Piccoli, F S, Ricca, T I, Dias, A A M, Coudry, R A, Galante, P A, Torres, C, Fahhan, L, Lourenço, S, Grundy, P E, de Camargo, B, de Souza, S, Neves, E J, Soares, F A, Brentani, H, Carraro, D M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223691/
https://ncbi.nlm.nih.gov/pubmed/22048167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.105
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