Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time

In laboratory studies, acquired resistance to long-term antihormonal therapy in breast cancer evolves through two phases over 5 y. Phase I develops within 1 y, and tumor growth occurs with either 17β-estradiol (E(2)) or tamoxifen. Phase II resistance develops after 5 y of therapy, and tamoxifen stil...

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Detaylı Bibliyografya
Asıl Yazarlar: Ariazi, Eric A., Cunliffe, Heather E., Lewis-Wambi, Joan S., Slifker, Michael J., Willis, Amanda L., Ramos, Pilar, Tapia, Coya, Kim, Helen R., Yerrum, Smitha, Sharma, Catherine G. N., Nicolas, Emmanuelle, Balagurunathan, Yoganand, Ross, Eric A., Jordan, V. Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223472/
https://ncbi.nlm.nih.gov/pubmed/22011582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115188108
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