Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time

In laboratory studies, acquired resistance to long-term antihormonal therapy in breast cancer evolves through two phases over 5 y. Phase I develops within 1 y, and tumor growth occurs with either 17β-estradiol (E(2)) or tamoxifen. Phase II resistance develops after 5 y of therapy, and tamoxifen stil...

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Detalhes bibliográficos
Main Authors: Ariazi, Eric A., Cunliffe, Heather E., Lewis-Wambi, Joan S., Slifker, Michael J., Willis, Amanda L., Ramos, Pilar, Tapia, Coya, Kim, Helen R., Yerrum, Smitha, Sharma, Catherine G. N., Nicolas, Emmanuelle, Balagurunathan, Yoganand, Ross, Eric A., Jordan, V. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223472/
https://ncbi.nlm.nih.gov/pubmed/22011582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115188108
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