The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

The G protein-coupled receptor GPR30 (GPER) binds 17β-estradiol (E(2)), yet differs from classical estrogen receptors (ERα and ERβ). GPR30 can mediate E(2)-induced non-genomic signaling, but its role in ERα-positive breast cancer remains unclear. Gene expression microarray data from 5 cohorts compri...

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Detalhes bibliográficos
Main Authors: Ariazi, Eric A., Brailoiu, Eugen, Yerrum, Smitha, Shupp, Heather A., Slifker, Michael J., Cunliffe, Heather E., Black, Michael A., Donato, Anne L., Arterburn, Jeffrey B., Oprea, Tudor I., Prossnitz, Eric R., Dun, Nae J., Jordan, V. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879282/
https://ncbi.nlm.nih.gov/pubmed/20086172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3068
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