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The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

The G protein-coupled receptor GPR30 (GPER) binds 17β-estradiol (E(2)), yet differs from classical estrogen receptors (ERα and ERβ). GPR30 can mediate E(2)-induced non-genomic signaling, but its role in ERα-positive breast cancer remains unclear. Gene expression microarray data from 5 cohorts compri...

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Bibliographische Detailangaben
Hauptverfasser: Ariazi, Eric A., Brailoiu, Eugen, Yerrum, Smitha, Shupp, Heather A., Slifker, Michael J., Cunliffe, Heather E., Black, Michael A., Donato, Anne L., Arterburn, Jeffrey B., Oprea, Tudor I., Prossnitz, Eric R., Dun, Nae J., Jordan, V. Craig
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879282/
https://ncbi.nlm.nih.gov/pubmed/20086172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3068
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