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IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells
Immune suppressive activities exerted by regulatory T-cell subsets have several specific functions, including self-tolerance and regulation of adaptive immune reactions, and their dysfunction can lead to autoimmune diseases and contribute to AIDS and cancer. Two functionally distinct regulatory T-ce...
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Auteurs principaux: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223453/ https://ncbi.nlm.nih.gov/pubmed/22065791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113301108 |
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