Vaccination with Tat toxoid attenuates disease in simian/HIV-challenged macaques

The Tat protein is essential for HIV type 1 (HIV-1) replication and may be an important virulence factor in vivo. We studied the role of Tat in viral pathogenesis by immunizing rhesus macaques with chemically inactivated Tat toxoid and challenging these animals by intrarectal inoculation with the si...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pauza, C. David, Trivedi, Parul, Wallace, Marianne, Ruckwardt, Tracy J., Le Buanec, Hélene, Lu, Wei, Bizzini, Bernard, Burny, Arséne, Zagury, Daniel, Gallo, Robert C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC16271/
https://ncbi.nlm.nih.gov/pubmed/10725402
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia