IFNα kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model

A major involvement of IFNα in the etiopathogenesis of systemic lupus erythematosus has been suggested by clinical observations, including the increase of serum levels of this cytokine in patients with active disease. Supporting this hypothesis, we have shown that expression of IFNα from a recombina...

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Autors principals: Zagury, Daniel, Le Buanec, Hélène, Mathian, Alexis, Larcier, Patrick, Burnett, Roger, Amoura, Zahir, Emilie, Dominique, Peltre, Gabriel, Bensussan, Armand, Bizzini, Bernard, Gallo, Robert C., Koutouzov, Sophie
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654395/
https://ncbi.nlm.nih.gov/pubmed/19279210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900615106
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