IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells

Immune suppressive activities exerted by regulatory T-cell subsets have several specific functions, including self-tolerance and regulation of adaptive immune reactions, and their dysfunction can lead to autoimmune diseases and contribute to AIDS and cancer. Two functionally distinct regulatory T-ce...

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Detalles Bibliográficos
Autores principales: Le Buanec, Hélène, Gougeon, Marie-Lise, Mathian, Alexis, Lebon, Pierre, Dupont, Jean-Michel, Peltre, Gabriel, Hemon, Patrice, Schmid, Michel, Bizzini, Bernard, Künding, Thomas, Burny, Arsène, Bensussan, Armand, Amoura, Zahir, Gallo, Robert C., Zagury, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223453/
https://ncbi.nlm.nih.gov/pubmed/22065791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113301108
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