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Glucocorticoid Regulation of SLIT/ROBO Tumour Suppressor Genes in the Ovarian Surface Epithelium and Ovarian Cancer Cells

The three SLIT ligands and their four ROBO receptors have fundamental roles in mammalian development by promoting apoptosis and repulsing aberrant cell migration. SLITs and ROBOs have emerged as candidate tumour suppressor genes whose expression is inhibited in a variety of epithelial tumours. We de...

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Detalhes bibliográficos
Main Authors: Dickinson, Rachel E., Fegan, K. Scott, Ren, Xia, Hillier, Stephen G., Duncan, W. Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223191/
https://ncbi.nlm.nih.gov/pubmed/22132142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027792
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